细胞培养与扩增 | Cell Culture and Expansion
三维细胞培养 | 3D Cell Culture
基质胶提供了类似于细胞外基质(ECM)的环境,使得细胞能够在三维空间中生长和扩展。这对于研究细胞行为、分化和相互作用非常重要。
Matrigel provides an ECM-like environment, allowing cells to grow and expand in three dimensions. This is crucial for studying cell behavior, differentiation, and interactions.
干细胞培养 | Stem Cell Culture
基质胶支持干细胞的生长和多能性保持,是干细胞培养的重要材料。特别是在胚胎干细胞和诱导多能干细胞的培养中,被广泛使用。
Matrigel supports the growth and maintenance of stem cells' pluripotency, making it an essential material for stem cell culture. It is widely used for culturing embryonic stem cells and induced pluripotent stem cells.
细胞分化与诱导 | Cell Differentiation and Induction
组织特异性分化 | Tissue-Specific Differentiation
基质胶可以通过模拟体内的微环境,诱导干细胞分化为特定的细胞类型,如神经细胞、肌肉细胞和肝细胞等。
Matrigel can simulate the in vivo microenvironment to induce stem cells to differentiate into specific cell types, such as neurons, muscle cells, and hepatocytes.
器官类器官培养 | Organoid Culture
基质胶用于培养类器官(organoids),这些三维细胞团能够模拟真实器官的结构和功能,适用于发育生物学和疾病模型研究。
Matrigel is used to culture organoids, three-dimensional cell clusters that can mimic the structure and function of real organs, suitable for developmental biology and disease modeling.
肿瘤研究 | Cancer Research
肿瘤模型构建 | Tumor Model Construction
基质胶常用于构建体外肿瘤模型,研究肿瘤细胞的增殖、侵袭和转移机制。
Matrigel is often used to construct in vitro tumor models to study the proliferation, invasion, and metastasis mechanisms of cancer cells.
药物筛选 | Drug Screening
基质胶提供的三维培养环境可以更真实地模拟体内肿瘤微环境,用于高通量药物筛选和抗肿瘤药物的疗效评估。
The 3D culture environment provided by Matrigel can more realistically simulate the in vivo tumor microenvironment, used for high-throughput drug screening and efficacy evaluation of anti-cancer drugs.
细胞迁移和侵袭研究 | Cell Migration and Invasion Studies
迁移实验 | Migration Assays
基质胶用于细胞迁移和侵袭实验,如划痕实验和Boyden小室实验,研究细胞在三维基质中的运动行为。
Matrigel is used in cell migration and invasion assays, such as scratch assays and Boyden chamber assays, to study cell movement behavior in a 3D matrix.
侵袭实验 | Invasion Assays
通过模拟基质屏障,研究细胞尤其是肿瘤细胞的侵袭能力和机制。
By simulating the matrix barrier, Matrigel is used to study the invasion capabilities and mechanisms of cells, particularly cancer cells.
血管生成研究 | Angiogenesis Research
血管生成模型 | Angiogenesis Models
基质胶可以支持内皮细胞在三维环境中形成血管样结构,用于研究血管生成机制和新型抗血管生成药物的筛选。
Matrigel can support the formation of blood vessel-like structures by endothelial cells in a 3D environment, used to study angiogenesis mechanisms and screen new anti-angiogenic drugs.
再生医学与组织工程 | Regenerative Medicine and Tissue Engineering
组织修复与再生 | Tissue Repair and Regeneration
基质胶在再生医学中用于支持细胞移植和组织修复,如皮肤、骨骼和神经等组织的再生。
Matrigel is used in regenerative medicine to support cell transplantation and tissue repair, such as the regeneration of skin, bone, and nerve tissues.
生物打印 | Bioprinting
基质胶作为生物墨水中的重要成分,用于三维生物打印技术,构建复杂的组织和器官结构。
Matrigel serves as an important component of bio-ink in 3D bioprinting technology, used to construct complex tissue and organ structures.
神经生物学研究 | Neurobiology Research
神经细胞培养 | Neuronal Cell Culture
基质胶用于神经细胞和神经祖细胞的培养和分化研究,模拟神经组织的微环境。
Matrigel is used for the culture and differentiation of neuronal cells and neural progenitor cells, simulating the neural tissue microenvironment.
神经网络形成 | Neuronal Network Formation
在基质胶中培养的神经细胞可以形成复杂的神经网络,用于研究神经信号传导和神经疾病机制。
Neuronal cells cultured in Matrigel can form complex neural networks, used to study neural signal transmission and the mechanisms of neurological diseases.