简介:盐酸异丙肾上腺素,Isoprenaline hydrochloride是一种非选择性的β-肾上腺素能受体激动剂,具有有效的外周血管扩张剂,支气管扩张剂和心脏刺激活性。
盐酸异丙肾上腺素物理化学性质:
密度 |
1.324 g/cm3 |
沸点 |
417.5ºC at 760 mmHg |
熔点 |
165-175 °C (dec.)(lit.) |
分子式 |
C11H18ClNO3 |
分子量 |
247.719 |
闪点 |
179.7ºC |
精确质量 |
247.097519 |
PSA |
72.72 |
LogP |
2.3221 |
外观性状 |
白色结晶粉末 |
储存条件 |
本品应密封于阴凉避光处保存。 |
稳定性 |
Stable, but may be air and light sensitive. Incompatible with strong oxidizing agents. |
水溶解性 |
Soluble |
盐酸异丙肾上腺素详细介绍:
中文名称: |
盐酸异丙肾上腺素 |
中文别名: |
盐酸异丙肾上腺素;异丙肾上腺素盐酸盐;4-[(2-异丙氨基-1-羟基)乙基]-1,2-苯二酚盐酸盐;盐酸异丙肾上腺素原药;异丙肾上腺素;异丙肾上腺素盐酸盐 USP标准品 |
英文名称: |
Isoproterenol hydrochloride |
英文别名: |
isoprenaline hydrochloride;Isoproterenol, HCl;2-benzenediol,4-(1-hydroxy-2-((1-methylethyl)amino)ethyl)-hydrochloride;3,4-dihydroxy-alpha-((isopropylamino)methyl)-benzylalcohohydrochloride;alpha-(isopropylaminomethyl)-3,4-dihydroxybenzylalcoholhydrochloride;euspiran;isadrine;isoprenalinechloride;isopropylnorepinephrine-hydrochloride;isoproterenolmonohydrochloride;Isoprenaline HCl;Isolated soy protein;Isoproterenol Hydrochloride;Isoproterenol (hydrochloride);[3H]-Isoproterenol hydrochloride;Isomenyl;isoprenaline;Isoprenaline (hydrochloride);Isovon;isuprel;Mistarel;proternol;Saventrine IV;Suscardia;(±)-Isoproterenol hydrochloride;1-(3′,4′-Dihydroxyphenyl)-2-isopropylaminoethanol hydrochloride;N-Isopropyl-DL-noradrenaline hydrochloride;3,4-Dihydroxy-alpha-((isopropylamino)methyl)-benzyl alcohol hydrochloride;4-(1-Hydroxy-2-((methylethyl)amino)ethyl)-1,2-benzenediol hydrochloride;Aludrine hydrochloride;Isoproterenol HCl;Aerolone;Aerotrol;Izadrin;Vapo-Iso;DL-Isoprenaline hydrochloride;DL-Isoproterenol hydrochloride;Isuprel hydrochloride;Asthpul;Norisodrine hydrochloride;Isopropylarterenol hydrochloride;dl-Isadrine hydrochloride;(+-)-Isoproterenol hydrochloride;Norisodrine Aerotrol;Isoprenaline chloride;Isoproterenol monohydrochloride;(+-)-Isoprenaline hydrochl |
CAS号: |
51-30-9 |
分子式: |
C11H18CLNO3 |
分子量: |
247.72 |
详细描述 |
博飞美科商城提供的[Sigma-Aldrich]Isoprenaline Hydrochloride为博飞美科出品的其它生化试剂,产品稳定,定制速度快,极大地方便了广大科研客户的使用需求。产品包装为25G,安全运输。 属性: mp:165-175 °C (dec.) (lit.) SMILES string:Cl.CC(C)NCC(O)c1ccc(O)c(O)c1 InChI:1S/C11H17NO3.ClH/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;/h3-5,7,11-15H,6H2,1-2H3;1H InChI key:IROWCYIEJAOFOW-UHFFFAOYSA-N 包装: 5, 25, 100 g in poly bottle 生化/生理作用: β-肾上腺素受体激活剂,增加胞质cAMP。 查询关键词:“51-30-9,盐酸异丙肾上腺素,Isoprenaline Hydrochloride,Sigma-Aldrich,上海现货,以Sigma官网为准”。 |
盐酸异丙肾上腺素参考文献:
[1]. Degerman E, et al. Evidence that insulin and isoprenaline activate the cGMP-inhibited low-Km cAMP phosphodiesterase in rat fat cells by phosphorylation. Proc Natl Acad Sci U S A. 1990 Jan;87(2):533-7
[2]. Vannucci SJ, et al. Cell surface accessibility of GLUT4 glucose transporters in insulin-stimulated rat adipose cells. Modulation by isoprenaline and adenosine. Biochem J. 1992 Nov 15;288 (Pt 1):325-30.
[3]. Delpy E, et al. Effects of cyclic GMP elevation on isoprenaline-induced increase in cyclic AMP and relaxation in rat aortic smooth muscle: role of phosphodiesterase 3. Br J Pharmacol. 1996 Oct;119(3):471-8.
[4]. Muller FU, et al. Isoprenaline stimulates gene transcription of the inhibitory G protein alpha-subunit Gi alpha-2 in rat heart. Circ Res. 1993 Mar;72(3):696-700.
[5]. Lei M, et al. Modulation of delayed rectifier potassium current, iK, by isoprenaline in rabbit isolated pacemaker cells. Exp Physiol. 2000 Jan;85(1):27-35.