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发布日期:2022/5/18 16:53:00

简介:盐酸异丙肾上腺素Isoprenaline hydrochloride是一种非选择性的β-肾上腺素能受体激动剂,具有有效的外周血管扩张剂,支气管扩张剂和心脏刺激活性。

盐酸异丙肾上腺素物理化学性质:

密度

1.324 g/cm3

沸点

417.5ºC at 760 mmHg

熔点

165-175 °C (dec.)(lit.)

分子式

C11H18ClNO3

分子量

247.719

闪点

179.7ºC

精确质量

247.097519

PSA

72.72

LogP

2.3221

外观性状

白色结晶粉末

储存条件

本品应密封于阴凉避光处保存。

稳定性

Stable, but may be air and light sensitive. Incompatible with strong oxidizing agents.

水溶解性

Soluble

 

盐酸异丙肾上腺素详细介绍:

中文名称:

盐酸异丙肾上腺素

中文别名:

盐酸异丙肾上腺素;异丙肾上腺素盐酸盐;4-[(2-异丙氨基-1-羟基)乙基]-1,2-苯二酚盐酸盐;盐酸异丙肾上腺素原药;异丙肾上腺素;异丙肾上腺素盐酸盐 USP标准品

英文名称:

Isoproterenol hydrochloride

英文别名:

isoprenaline hydrochloride;Isoproterenol, HCl;2-benzenediol,4-(1-hydroxy-2-((1-methylethyl)amino)ethyl)-hydrochloride;3,4-dihydroxy-alpha-((isopropylamino)methyl)-benzylalcohohydrochloride;alpha-(isopropylaminomethyl)-3,4-dihydroxybenzylalcoholhydrochloride;euspiran;isadrine;isoprenalinechloride;isopropylnorepinephrine-hydrochloride;isoproterenolmonohydrochloride;Isoprenaline HCl;Isolated soy protein;Isoproterenol Hydrochloride;Isoproterenol (hydrochloride);[3H]-Isoproterenol hydrochloride;Isomenyl;isoprenaline;Isoprenaline (hydrochloride);Isovon;isuprel;Mistarel;proternol;Saventrine IV;Suscardia;(±)-Isoproterenol hydrochloride;1-(3′,4′-Dihydroxyphenyl)-2-isopropylaminoethanol hydrochloride;N-Isopropyl-DL-noradrenaline hydrochloride;3,4-Dihydroxy-alpha-((isopropylamino)methyl)-benzyl alcohol hydrochloride;4-(1-Hydroxy-2-((methylethyl)amino)ethyl)-1,2-benzenediol hydrochloride;Aludrine hydrochloride;Isoproterenol HCl;Aerolone;Aerotrol;Izadrin;Vapo-Iso;DL-Isoprenaline hydrochloride;DL-Isoproterenol hydrochloride;Isuprel hydrochloride;Asthpul;Norisodrine hydrochloride;Isopropylarterenol hydrochloride;dl-Isadrine hydrochloride;(+-)-Isoproterenol hydrochloride;Norisodrine Aerotrol;Isoprenaline chloride;Isoproterenol monohydrochloride;(+-)-Isoprenaline hydrochl

CAS号:

51-30-9

分子式:

C11H18CLNO3

分子量:

247.72

详细描述

博飞美科商城提供的[Sigma-Aldrich]Isoprenaline Hydrochloride为博飞美科出品的其它生化试剂,产品稳定,定制速度快,极大地方便了广大科研客户的使用需求。产品包装为25G,安全运输。

属性:

mp:165-175 °C (dec.) (lit.)

SMILES string:Cl.CC(C)NCC(O)c1ccc(O)c(O)c1

InChI:1S/C11H17NO3.ClH/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;/h3-5,7,11-15H,6H2,1-2H3;1H

InChI key:IROWCYIEJAOFOW-UHFFFAOYSA-N

包装:

5, 25, 100 g in poly bottle

生化/生理作用:

β-肾上腺素受体激活剂,增加胞质cAMP。

查询关键词:51-30-9盐酸异丙肾上腺素Isoprenaline HydrochlorideSigma-Aldrich,上海现货,以Sigma官网为准

 

盐酸异丙肾上腺素参考文献:

[1]. Degerman E, et al. Evidence that insulin and isoprenaline activate the cGMP-inhibited low-Km cAMP phosphodiesterase in rat fat cells by phosphorylation. Proc Natl Acad Sci U S A. 1990 Jan;87(2):533-7

[2]. Vannucci SJ, et al. Cell surface accessibility of GLUT4 glucose transporters in insulin-stimulated rat adipose cells. Modulation by isoprenaline and adenosine. Biochem J. 1992 Nov 15;288 (Pt 1):325-30.

[3]. Delpy E, et al. Effects of cyclic GMP elevation on isoprenaline-induced increase in cyclic AMP and relaxation in rat aortic smooth muscle: role of phosphodiesterase 3. Br J Pharmacol. 1996 Oct;119(3):471-8.

[4]. Muller FU, et al. Isoprenaline stimulates gene transcription of the inhibitory G protein alpha-subunit Gi alpha-2 in rat heart. Circ Res. 1993 Mar;72(3):696-700.

[5]. Lei M, et al. Modulation of delayed rectifier potassium current, iK, by isoprenaline in rabbit isolated pacemaker cells. Exp Physiol. 2000 Jan;85(1):27-35.

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