简介:阿德福韦酯片,Adefovir Dipivoxil可阻断HBV逆转录酶。
阿德福韦酯片物理化学性质:
密度 |
1.4±0.1 g/cm3 |
沸点 |
641.0±65.0 °C at 760 mmHg |
熔点 |
98-102ºC |
分子式 |
C20H32N5O8P |
分子量 |
501.47 |
闪点 |
341.5±34.3 °C |
精确质量 |
501.198853 |
PSA |
176.79 |
LogP |
2.45 |
蒸汽压 |
0.0±1.9 mmHg at 25°C |
折射率 |
1.569 |
储存条件 |
−20°C |
阿德福韦酯片详细介绍:
中文名称: |
阿德福韦酯片 |
中文别名: |
阿德福韦酯片;9-[2-[双(新戊酰氧基)甲氧基]磷酰甲氧基]乙基-腺嘌呤;阿德伏韦酯;阿德幅韦二脂;阿地福韦双吡呋酯;阿的福韦酯;阿地福韦酯;阿德福韦酯;9-[2-[双(新戊酰氧基)甲氧基]磷;Adefovir Dipivoxil 阿德福韦酯;阿达帕林;阿德伏韦酯,阿德福韦酯,阿德福韦酯片;阿德福韦脂;阿德福韦脂(ADV);培美曲塞二钠;9-[2-[二(特戊酰氧基)甲基]氧膦基]甲氧基]乙基]腺嘌呤 中文同义词: 阿德福韦酯;阿地福 |
英文名称: |
Adefovir dipivoxil |
英文别名: |
Adefovir Dipivoxyl;9-[2-[bis[(pivaloyloxy)methoxy]phosphinyl]methoxy]ethyl]adenine;ADEFOVIR PIVOXIL;BIS(PIVALOYLOXYMETHYL)-9-[2-(PHOSPHONOMETHOXY)ETHYL]ADENINE;BIS POM PMEA;Bis(Pivaloyloxymethyl)-9-[(R)-2-(Phosphonomethoxy)Ethyl]Adenine;Adefovir Dipivoxl;ADEFOVIR DIPVOXIL;ADEFOVIR DIPIVOLIX;ADEFOVIR;PHARMA-0062;Adefovir Dipivoxil;((((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)phosphoryl)-bis(oxy))bis(methylene) bis(2,2-dimethylpropanoate);GS 0840;9-(2[bis(Pivaloyloxymethoxy)phosphorylmethoxy]ethyl)adenine;9-[2-[Bis(pivaloyloxymethoxy)phosphorylmethoxy]ethyl]adenine;Adefovir Dipivoxi;Hepsera;Preveon;bis-POM PMEA;Adefovirdipivoxl;GS 840;[2-(6-aminopurin-9-yl)ethoxymethyl-(2,2-dimethylpropanoyloxymethoxy)phosphoryl]oxymethyl 2,2-dimethylpropanoate;C20H32N5O8P;Adefovir dipivoxil [USAN];Adefovir dipivoxil (USAN);U6Q8Z01514;Adefovir Dipivoxil (Preveon, Hepsera);(((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)phosphinylidene)bis(oxymethylene) 2,2-dimethylpropanoate;NCGC |
CAS号: |
142340-99-6 |
分子式: |
C20H32N5O8P |
分子量: |
501.47 |
详细描述: |
博飞美科提供142340-99-6,阿德福韦酯片,Adefovir Dipivoxil,Perfemiker,上海现货。 Perfemiker,致力于提供高品质、高性价比小分子化合物的产品。 Perfemiker小分子化合物大量库存,提供超过2万种的抑制剂、激动剂、拮抗剂等产品,是药物及疾病研究的重要原料供应商。 逆转录酶抑制剂,Adefovir Dipivoxil可阻断HBV逆转录酶。 查询关键词:“142340-99-6,阿德福韦酯片,Adefovir Dipivoxil,Perfemiker,上海现货”。 |
阿德福韦酯片参考文献:
[1]. Marcellin, P., et al., Adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B. N Engl J Med, 2003. 348(9): p. 808-16.
[2]. Manolakopoulos, S., et al., Long-term therapy with adefovir dipivoxil in hepatitis B e antigen-negative patients developing resistance to lamivudine. Aliment Pharmacol Ther, 2008. 27(3): p. 266-73.
[3]. Committee, A.I.S., A randomized placebo-controlled trial of adefovir dipivoxil in advanced HIV infection: the ADHOC trial. HIV Med, 2002. 3(4): p. 229-38.
[4]. Fisher, E.J., et al., The safety and efficacy of adefovir dipivoxil in patients with advanced HIV disease: a randomized, placebo-controlled trial. AIDS, 2001. 15(13): p. 1695-700.