简介:伏波酯,Phorbol 12-myristate 13-acetate (PMA)是一种佛波酯,是常用的 PKC 活化剂。
伏波酯物理化学性质:
密度 |
1.2±0.1 g/cm3 |
沸点 |
698.1±55.0 °C at 760 mmHg |
分子式 |
C36H56O8 |
分子量 |
616.825 |
闪点 |
208.1±25.0 °C |
精确质量 |
616.397522 |
PSA |
130.36 |
LogP |
7.71 |
外观性状 |
白色至灰白色固体 |
蒸汽压 |
0.0±5.0 mmHg at 25°C |
折射率 |
1.553 |
储存条件 |
库房通风低温干燥,与食品分开储运 |
水溶解性 |
DMSO: DMSO solutions can be stored dark at −20?#x00b0;C for at least six months.soluble |
伏波酯详细介绍:
中文名称: |
伏波酯 |
中文别名: |
佛波醇12-十四酸酯13-乙酸酯;佛波酯;12-O-十四烷酰佛波-13醋酸酯;12-O-十四烷酰佛波醇-13-乙酸酯;12-O-十四烷酰佛波醋酸酯-13;12-豆蔻酸-13-乙酸佛波醇;12-十四酸酯13-乙酸佛波醇酯;PKC激动剂;佛波醇;佛波醇-12-十四酸酯-13-乙酸酯;佛波酯 PMA;伏波酯;乙酸佛波酯;PMA 佛波酯;豆蔻酰佛波醇乙酯;乙酸佛波酯 PMA;佛波脂酸(5MG/ML) |
英文名称: |
Phorbol 12-myristate 13-acetate |
英文别名: |
Tetradecanoic acid,(1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-(acetyloxy)-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1H-cyclopropa[3,4]benz[1,2-e]azulen-9-ylester;12-O-tetradecanoyl phorbol-13-acetate;4β-Phorbol 12-Myristate 13-Acetate;Invivogen;PHORBOL 12-MYRISTATE 13-ACETATE;PMA;PMA (TPA,Cocarcinogen A1,12-O-Tetradecanoyl-phorbol 13-Acetate,Phorbol 12-myristate 13-acetate);Tetradecanoic acid,(1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-(acetyloxy)-1a,1b,4,4a,5,7a,7b,8,9,9a-de...;12-O-Tetradecanoylphorbol 13-acetate;4β,9α,12β,13α,20-Pentahydroxytiglia-1,6-dien-3-one 12-tetradecanoate 13-acetate;TPA;12-o-tetradecanoyl phorbol acetate;factora1;Cocarcinogen A1;Cocarcinogen C3;pma(tumorpromoter);factora1[crotonoil];factora1(crotonoil);phorbolmyristateacetate;phorbolacetate,myristate;12-O-Tetradecanoylphorbol-13-acetate;,9aalpha))-;Factor A1;Phorbol myristate acetate;Factor A1 (croton oil);Phorbol ester;Tetradecanoylphorbol acetate;PMA (tumor promot |
CAS号: |
16561-29-8 |
分子式: |
C36H56O8 |
分子量: |
616.83 |
详细描述: |
博飞美科提供16561-29-8,伏波酯,12-O-tetradecanoyl phorbol-13-acetate (PMA),Perfemiker,上海现货。 Perfemiker,致力于提供高品质、高性价比小分子化合物的产品。 Perfemiker小分子化合物大量库存,提供超过2万种的抑制剂、激动剂、拮抗剂等产品,是药物及疾病研究的重要原料供应商。 ERK/MAPK激活剂,Phorbol 12-myristate 13-acetate (PMA) 是一种佛波酯,是常用的 PKC 活化剂。 查询关键词:“16561-29-8,伏波酯,12-O-tetradecanoyl phorbol-13-acetate (PMA),Perfemiker,上海现货”。 |
伏波酯参考文献:
[1]. Xu F, et al. Protein kinase C-mediated Ca2+ entry in HEK 293 cells transiently expressing human TRPV4. Br J Pharmacol. 2003 Sep;140(2):413-21.
[2]. Mugami S, et al. Differential roles of PKC isoforms (PKCs) and Ca2+ in GnRH and phorbol 12-myristate 13-acetate (PMA) stimulation of p38MAPK phosphorylation in immortalized gonadotrope cells. Mol Cell Endocrinol. 2017 Jan 5;439:141-154.
[3]. Hou S, et al. Mechanism of Mitochondrial Connexin43's Protection of the Neurovascular Unit under Acute Cerebral Ischemia-Reperfusion Injury. Int J Mol Sci. 2016 May 5;17(5). pii: E679.
[4]. Zhang T, et al. MPTP-Induced Dopamine Depletion in Basolateral Amygdala via Decrease of D2R Activation Suppresses GABAA Receptors Expression and LTD Induction Leading to Anxiety-Like Behaviors. Front Mol Neurosci. 2017 Aug 7;10:247.