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简介：脱水穿心莲内酯，Dehydroandrographolide是从中草药穿心莲提取的天然化合物，具有抗感染活性。
脱水穿心莲内酯物理化学性质：
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密度 |
1.2±0.1 g/cm3 |
|
沸点 |
512.8±50.0 °C at 760 mmHg |
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分子式 |
C20H28O4 |
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分子量 |
332.43 |
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闪点 |
178.3±23.6 °C |
|
PSA |
86.99 |
|
LogP |
2.97 |
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蒸汽压 |
0.0±3.0 mmHg at 25°C |
|
折射率 |
1.584 |
脱水穿心莲内酯详细介绍：
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中文名称： |
脱水穿心莲内酯 |
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中文别名： |
脱水穿心莲内酯;穿心莲丁素;zzstandard 品牌 脱水穿心莲内酯对照品;丙二酸二异丙酯;穿心莲浸膏;穿心莲内酯;穿心莲脱水内酯;二氢杨梅素;脱氢穿心莲内酯(RG);脱水穿心莲内酯 Dehydroandrographolide;脱水穿心莲内酯 标准品;脱水穿心莲内酯（标准品）;脱水穿心莲内酯(穿心莲丁素);脱水穿心莲内酯对照品;脱氧野尻霉素;川贝母;穿心莲总内酯干浸膏,穿心莲丁素;分析对照品 |
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英文名称： |
Dehydroandrographolide |
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英文别名： |
Dehydroandrographolide;ANDROGRAPHOLIDE, DEHYDRO-;14-Deoxy-11-dehydroandrographolide;Dehydroandrographoline;14-(P);DEOXY-11,12-DIDEHYDROANDROGRAPHOLIDE;Dehydroanddrographolide;(3E)-3-[2-[(1S,4aS,5R,6R,8aS)-Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]-2(3H)-furanone;2(3H)-Furanone, 3-[2-[(1S,4aS,5R,6R,8aS)-decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]-, (3E)-;ANDROGRAPHOLIDE, DEHYDRO(RG);Dehydrographkide;6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]-,(3E);ANDROGRAPHOLIDE,DEHYDRO |
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CAS号： |
134418-28-3 |
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分子式： |
C20H28O4 |
|
分子量： |
332.43 |
|
详细描述： |
博飞美科提供134418-28-3，脱水穿心莲内酯，Dehydroandrographolide，Perfemiker，上海现货。 Perfemiker，致力于提供高品质、高性价比小分子化合物的产品。 Perfemiker小分子化合物大量库存，提供超过2万种的抑制剂、激动剂、拮抗剂等产品，是药物及疾病研究的重要原料供应商。 脱水穿心莲内酯(Dehydroandrographolide)是从中草药穿心莲提取的天然化合物，具有抗感染活性。 查询关键词:“134418-28-3，脱水穿心莲内酯，Dehydroandrographolide，Perfemiker，上海现货”。 |
脱水穿心莲内酯参考文献：
[1]. Chen Q, et al. Pharmacokinetics and tolerance of dehydroandrographolide succinate injection after intravenous administration in healthy Chinese volunteers. Acta Pharmacol Sin. 2012 Oct;33(10):1332-6.
[2]. Chao WW, et al. Isolation and identification of bioactive compounds in Andrographis paniculata (Chuanxinlian). Chin Med. 2010 May 13;5:17.
[3]. Basak A, et al. Inhibition of proprotein convertases-1, -7 and furin by diterpines of Andrographis paniculata and their succinoyl esters. Biochem J. 1999 Feb 15;338 ( Pt 1):107-13.
[4]. Zhu T, et al. Dehydroandrographolide succinate inhibits oxidative stress in mice with lipopolysaccharide-induced acute lung injury by inactivating iNOS. Nan Fang Yi Ke Da Xue Xue Bao. 2012 Sep;32(9):1238-41.
[5]. Chen H, et al. Synthesis, structure-activity relationships and biological evaluation of dehydroandrographolide and andrographolide derivatives as novel anti-hepatitis B virus agents. Bioorg Med Chem Lett. 2014 May 15;24(10):2353-9.
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